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PITX2 — RAC1
Text-mined interactions from Literome
Wei et al., Mol Biol Cell 2002
:
Moreover,
Pitx2a expression
resulted in activation of the Rho GTPases
Rac1 and RhoA, and the dominant negative Rac1 mutant N17Rac1 inhibited cell spreading and disrupted localization of beta-catenin to the sites of cell-cell contacts
Fujii et al., J Biol Chem 2005
:
Because
p115-RGS suppressed Ang II-induced
Rac activation, Ang II receptor coupled Galpha(12/13) mediated NFAT activation through ROS production by Rac activation