Jordan et al., Genes Immun 2007
:
IFN-lambda1 was able to alter cytokine mediated Th biasing and when naive T cells were exposed to allogeneic mDC that had been matured in the presence of IFN-lambda1, secreted IL-13 was again markedly and consistently reduced , whereas secreted IFN-gamma was largely unaltered
Srinivas et al., Immunology 2008
:
Our results reveal that IFN-lambda1 preferentially inhibits IL-13 production, compared with IL-4 or IL-5