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CD4 — MYD88
Text-mined interactions from Literome
Franklin et al., Microbes Infect 2007
(Malaria...) :
MyD88 dependent activation of dendritic cells and
CD4 ( + ) T lymphocytes mediates symptoms, but is not required for the immunological control of parasites during rodent malaria
Zhou et al., J Virol 2009
(Arenaviridae Infections) :
Overall, these studies reveal a previously unknown
role of
MyD88 dependent signaling in CD4 ( + ) T cells in the regulation of the virus-specific
CD4 ( + ) T-cell response and in viral infection induced immunopathology in the central nervous system
Letran et al., Eur J Immunol 2011
:
Surprisingly, the adaptor molecule
Myd88 was not
required for robust
CD4 ( + ) T-cell responses to flagellin, indicating that TLR5 enhances flagellin-specific CD4 ( + ) T-cell responses in the absence of conventional TLR signaling