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IGF1 — ZNF143
Text-mined interactions from Literome
Paek et al., Exp Mol Med 2010
(Colonic Neoplasms) :
IGF-1 induces expression of
zinc-finger protein 143 in colon cancer cells through phosphatidylinositide 3-kinase and reactive oxygen species ... Taken together, these data suggest that
IGF-1 induces
ZNF143 expression in cancer cells via PI3-kinase and reactive oxygen species generation during receptor internalization
Paek et al., Mol Cells 2011
(Colonic Neoplasms) :
GAIP interacting protein, C-terminus is involved in the induction of
zinc-finger protein 143 in
response to
insulin-like growth factor-1 in colon cancer cells ... The knockdown of GIPC in colon cancer cells reduced
ZNF143 expression in
response to
IGF-1 ... IGF-1 signaling through its receptor, leading to the phosphorylation and activation of the PI3-kinase-Akt pathway and mitogenactivated protein kinases ( MAPKs ) was unaffected by the knockdown of GIPC, indicating the independence of the GIPC linked pathway from PI3-kinase- and MAPK linked signaling in
IGF-1 induced
ZNF143 expression