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NT5E — TNF
Text-mined interactions from Literome
Kalsi et al., Mol Cell Biochem 2002
:
Regulation of
ecto-5'-nucleotidase by
TNF-alpha in human endothelial cells
Peng et al., FASEB J 2008
(Disease Models, Animal...) :
After CCl ( 4 ) treatment, the mRNA level of A ( 1 ), A ( 2A ), A ( 2B ), and A ( 3 ) adenosine receptors,
tumor necrosis factor-alpha , interleukin (IL) -1beta, IL-13r alpha1, matrix metalloproteinase (MMP)-2, MMP-14, tissue inhibitor of metalloproteinase ( TIMP ) -1, and TIMP-2, and IL-13 level
increased markedly in both
CD73KO and WT mice, but Col1 alpha1, Col3 alpha1, and transforming growth factor-beta1 mRNA increased much more in WT mice than that in KO mice
Savic et al., Immunology 1990
:
IL-1 beta and
TNF-alpha stimulated mesangial cell
5'-nucleotidase activity in a dose dependent manner after treatment for 24 hr. Maximum increases reached 4.5 times and 1.7 times basal values for IL-1 beta ( 20 U/ml ) and TNF-alpha ( 25 ng/ml ), respectively
Doherty et al., Eur J Immunol 2012
(Inflammatory Bowel Diseases) :
Expression of
CD73 by peripheral CD4 ( + ) T cells was
increased by
TNF , and decreased by an anti-TNF monoclonal antibody ( infliximab )
Stefanovic et al., Ren Physiol Biochem 1995
:
Interleukin-1,
tumor necrosis factor , cyclic adenosine monophosphate and adenosine analogues also
activated 5'-nucleotidase whereas they were inactive on alkaline phosphodiesterase I