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HDAC1 — KLF4

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: HDAC1 — KLF4 (direct interaction, pull down) Noti et al., J Biol Chem 2005*

Text-mined interactions from Literome

Chen et al., J Nutr 2004 (Adenocarcinoma...) : Overexpression of HDAC1 significantly attenuated transcriptional activation of the KLF4 promoter by butyrate or TSA
Kee et al., J Mol Cell Cardiol 2009 (Cardiomegaly) : These results suggest that KLF4 , a novel anti-hypertrophic transcriptional regulator, mediates the HDAC inhibitor induced prevention of cardiac hypertrophy
Huang et al., Mol Pharmacol 2011 : This finding, together with the HDAC inhibitor induced up-regulation of KLF4 and E-cadherin, suggests that HDAC inhibitors could activate the expression of these genes through changes in histone methylation status
Kim et al., Am J Physiol Cell Physiol 2012 (MAP Kinase Signaling System) : CPI-17 transcription was insensitive to knockdown of myocardin/Kruppel-like factor 4 small interfering RNA or histone deacetylase inhibition