Gene interactions and pathways from curated databases and text-mining

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CXCL13 — MMP9

Text-mined interactions from Literome

Hu et al., Cancer Sci 2008 (Neoplasm Invasiveness...) : Furthermore, in contrast to CXCL12, which enhanced the activity of matrix metalloproteinase (MMP) 9 and MMP2 in PC3 and LNCap, CXCL16 ligation resulted in stronger MMP9 and MMP2 activity in LNCap but not in PC3
Pandruvada et al., Int J Cancer 2010 (Carcinoma, Squamous Cell...) : Interestingly, CXCL13 treatment to OSCC cells induced CXCR5 and MMP-9 expression suggesting an autocrine regulatory function in OSCC cells
Jovanović et al., Reproduction 2010 : Exogenous IL8/CXCL8 increased trophoblast cell migration and invasion, which may be partly attributable to stimulation of MMP2 and MMP9 levels and an increase in integrins
El Haibi et al., Molecular cancer 2010 (Prostatic Neoplasms) : We have previously shown that PCa tissue and cell lines express high levels of the chemokine receptor CXCR5, than compared to their normal counterparts, and interaction of CXCR5 with its specific ligand ( CXCL13 ) promoted PCa cell invasion, migration, and differential matrix metalloproteinase ( MMP ) expression
Laird et al., Hum Reprod 2011 : In contrast to its effects in other cells, CXCL12 had no effect on MMP-2 or MMP-9 production by endometrial stromal or epithelial cells