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Figueroa et al., Exp Hematol 2002
(Anoxia) :
Inhibition of NF-kappaB with a superrepressor dominant negative IkappaBalpha genetic construct also significantly blocked NF-kappaB and HIF-1 transactivation, as well as EPO gene expression
Lee et al., Biochem Biophys Res Commun 2004
:
EPO receptor mediated ERK kinase and NF-kappaB activation in erythropoietin promoted differentiation of astrocytes ... Conversely, treatment with anti-EPO and EPO receptor antibodies also reduced EPO induced ERK ( 2 ) and NF-kappaB activation
Carvalho et al., Oncogene 2005
(Carcinoma, Renal Cell...) :
Inhibition of JAK2, one of the receptor-proximal elements of EPO mediated signal transduction, greatly diminished the EPO mediated chemosensitization and NF-kappaB inhibition