Gene interactions and pathways from curated databases and text-mining

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IL8 — MYLIP

Text-mined interactions from Literome

Stanczyk et al., Arthritis Rheum 2008 (Arthritis, Rheumatoid) : Constitutive expression of both miR-155 and miR-146a was higher in RASFs than in those from patients with osteoarthritis ( OA ), and expression of miR-155 could be further induced by TNFalpha, interleukin-1beta , lipopolysaccharide, poly ( I-C ), and bacterial lipoprotein
Xiao et al., J Infect Dis 2009 (Helicobacter Infections...) : Furthermore, the overexpression of miR-155 negatively regulated the release of interleukin-8 and growth related oncogene-alpha
Bhaumik et al., Aging 2009 : Indeed, ectopic expression of miR-146a/b in primary human fibroblasts suppressed IL-6 and IL-8 secretion and downregulated IRAK1, a crucial component of the IL-1 receptor signal transduction pathway
Larner-Svensson et al., Respir Res 2010 : Functional studies indicated that IL-1beta induced miR-146a expression does not negatively regulate IL-6 and IL-8 release or basal proliferation ... Unlike previous reports, studies using miRNA inhibitors showed that miR-146a expression did not regulate IL-6 and IL-8 release or proliferation and suggest miR-146a function and mechanism is cell-type dependent
Majid et al., Cancer 2010 (Neoplasm Invasiveness...) : In this study, the authors demonstrated that miRNA-205 (miR-205) induced the expression the interleukin ( IL ) tumor suppressor genes IL24 and IL32 by targeting specific sites in their promoters
Hu et al., J Biol Chem 2011 (Breast Neoplasms...) : miR-520b regulates migration of breast cancer cells by targeting hepatitis B X-interacting protein and interleukin-8 ... In addition, we found that miR-520b could indirectly regulate IL-8 transcription by targeting HBXIP ... Thus, we conclude that miR-520b is involved in regulating breast cancer cell migration by targeting HBXIP and IL-8 via a network in which HBXIP promotes migration by stimulating NF-?B mediated IL-8 expression
Dai et al., Mol Hum Reprod 2012 (Endometriosis) : Accompanied by IKKß reduction, miR-199a suppressed nuclear factor-kappa B ( NF-?B ) pathway activation and interleukin-8 (IL-8) production in ESCs
Xu et al., J Immunol 2013 (Psoriasis) : Specific inhibition of miR-31 suppressed NF-?B-driven promoter luciferase activity and the basal and TNF-a induced production of IL-1ß, CXCL1/growth related oncogene-a, CXCL5/epithelial derived neutrophil activating peptide 78, and CXCL8/IL-8 in human primary keratinocytes
Tsuchiya et al., J Interferon Cytokine Res 2013 (Cystic Fibrosis...) : However, whether infection induced IL-8 expression in CF cells is also mediated by miR-155 is not known
Kuo et al., PloS one 2013 (Asthma...) : This increase of IL-8 secretion was due to an elevated microRNA-155 (miR-155) expression, which caused the suppression of Src homology 2 domain containing inositol 5-phosphatase 1 ( SHIP1 ) production and the subsequent activation of JNK signaling