Gene interactions and pathways from curated databases and text-mining

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CCL4 — TNF

Text-mined interactions from Literome

Dekkers et al., Infect Immun 1999 (Endotoxemia) : Divergent roles of tumor necrosis factor and platelet activating factor in endotoxin induced release of monocyte chemoattractant protein 1 and macrophage inflammatory protein 1beta in chimpanzees
Weber et al., Crit Rev Toxicol 2003 (Carbon Tetrachloride Poisoning...) : At the molecular level CCl4 activates tumor necrosis factor (TNF)alpha , nitric oxide ( NO ), and transforming growth factors ( TGF ) -alpha and -beta in the cell, processes that appear to direct the cell primarily toward ( self- ) destruction or fibrosis
Ishikado et al., Biol Pharm Bull 2005 (Carbon Tetrachloride Poisoning...) : Oral pretreatment of liposomal lactoferrin exhibited more suppressive effects than did non-liposomal lactoferrin on CCl4 induced hepatic injury in rats as well as on lipopolysaccharide induced TNF-alpha production from mouse peripheral blood mononuclear leukocytes
Wong et al., Allergy 2006 : The induction of RANTES by SCF or TNF-alpha was mediated by ERK and NF-kappaB, respectively, and SCF induced MIP-1beta release was mediated by ERK
Yang et al., World J Gastroenterol 2006 (Drug-Induced Liver Injury...) : We also found that GLPG reduced TNF-alpha level induced by CCl4 in the plasma of mice, whereas increased SOD activity in the rat serum
Machado et al., Microbes Infect 2008 : Interestingly, T. cruzi infected NOS2-deficient CMs produced significantly higher levels of CCL2, CCL4 , CCL5 and CXL2 in the presence of IFN-gamma and TNF
Guerrero-Plata et al., J Immunol 2009 (Acute Disease...) : In vitro infection of lung DC indicated that in pDC, production of IFN-alpha, TNF-alpha , and CCL5 was induced only by hMPV, whereas CCL3 and CCL4 were induced by both viruses
Leung et al., Histol Histopathol 2011 (Liver Cirrhosis, Experimental) : Treatment with L-arginine or SMT showed a significant reduction in CCl4 induced expression of these pro-fibrogenic factors, TNF-a and COX-2
Ebaid et al., Nutrition & metabolism 2013 : Furthermore, the CCl4 induced upregulation of TNF-a and Fas mRNA expression was significantly restored by the three treatments
McManus et al., J Immunol 1998 : In response to LPS, TNF-alpha , or IL-1 beta, both MIP-1 alpha and MIP-1 beta were induced at the mRNA and protein levels in a dose- and time dependent manner