Gene interactions and pathways from curated databases and text-mining

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DDIT3 — IL8

Text-mined interactions from Literome

Vij et al., Am J Respir Cell Mol Biol 2008 (Cystic Fibrosis) : We confirmed the regulation of IL-8 promoter by CHOP in CF cells using the IL-8 reporter assay
Cucinotta et al., J Biol Chem 2008 : We have previously shown that in human T lymphocytes the CHOP phosphorylation induced by prostaglandin E ( 2 ) ( PGE ( 2 ) ) -increased interleukin-8 (IL-8) gene expression ... Given the CHOP positive role in the regulation of transcription, here we have investigated the molecular mechanism ( s ) by which CHOP increases IL-8 gene activity under PGE ( 2 ) stimulus
Park et al., J Biol Chem 2010 : CHOP was positively involved in ER-activated IL-8 production and was negatively associated with expression of peroxisome proliferator activated receptor ? ( PPAR? )