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HMOX1 — IL8
Text-mined interactions from Literome
Loboda et al., Cell Mol Biol Incl Cyto Enzymol 2005
:
Heme oxygenase-1 dependent and -independent regulation of angiogenic genes expression : effect of cobalt protoporphyrin and cobalt chloride on VEGF and
IL-8 synthesis in human microvascular endothelial cells ... CoPPIX
induced HO-1 expression and strongly enhanced VEGF and IL-8 synthesis, through the activation of VEGF and
IL-8 promoters
Loboda et al., Antioxid Redox Signal 2009
:
However, neither overexpression of
HO-1 nor HO-1 inhibition
affected IL-8 synthesis
Lee et al., J Agric Food Chem 2013
(Diabetes Mellitus, Type 2) :
It was found that monascin promoted
heme oxygenase-1 (HO-1) expression
mediated by Nrf2. Suppressions of AGEs, tumor necrosis factor-a (TNF-a), and
interleukin-1ß ( IL-ß ) in serum of MG-induced rats were attenuated in the monascin administration group treated with retinoic acid ( RA )
Collino et al., Dis Model Mech 2013
(Disease Models, Animal...) :
Besides, chronic
HO-1 activation
suppressed the elevated levels of myeloperoxidase (MPO) activity,
interleukin 1ß (IL-1ß) production and tumor necrosis factor-a (TNFa) production that were evoked by the ischemic injury, and increased the plasma level of the anti-inflammatory cytokine IL-10
Das et al., J Antimicrob Chemother 2013
(Leishmaniasis, Visceral) :
Furthermore,
HO-1 blockade by miltefosine led to suppression of interleukin-10 and transforming growth factor-ß, but
enhanced interleukin-12 and tumour necrosis factor-a production, in VL patients