Gene interactions and pathways from curated databases and text-mining

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IL8 — PLAU

Text-mined interactions from Literome

Michi et al., Oral Oncol 2000 (Carcinoma, Squamous Cell...) : In contrast, neither anti-interleukin-8 (IL-8) antibody nor anti-hepatocyte growth factor ( HGF beta ) antibody affected uPA activity in the endothelial cells
Han et al., J Surg Res 2002 : In this report, we show that interleukin-8 (IL-8) , but not other cytokines tested, is a potent inducer of the 38-kDa uPA in organ cultured human skin ... In addition, the uPA inhibitor, PAI-1, was not affected by IL-8 ... The mRNA expression of uPA in the keratinocytes was found to be constitutively elevated and was not affected by IL-8
So et al., Gynecol Oncol 2004 (Neoplasm Invasiveness...) : IL-8 did not affect cellular migration, MMP2 activation, or uPA expression
Dulak et al., Endothelium : journal of endothelial cell research 2005 : Importantly, atorvastatin at the micromolar concentrations diminished the production of interleukin (IL)-8 , a proinflammatory and proangiogenic chemokine, and inhibited the synthesis of urokinase plasminogen activator (uPA) , a potent proinflammatory mediator