Gene interactions and pathways from curated databases and text-mining

◀ Back to IFNG

IFNG — IL1RN

Text-mined interactions from Literome

Danis et al., Clin Exp Immunol 1995 : This was especially evident when cytokines were used in combination with GM-CSF : IFN-gamma down-regulated production of IL-1Ra while up-regulating the production of IL-1 alpha/beta, IL-6 and TNF-alpha, while IL-4 had the exact opposite effect
Re et al., Eur J Immunol 1993 : Secretion of IL-1ra was induced in PMN treated with LPS, IL-4 and GM-CSF, but not by IL-1 beta, IFN-gamma and fMLP, thus yielding results that paralleled those seen in Northern blot experiments
Ruth et al., J Immunol 1996 (Granuloma) : In vivo depletion of IL-4, IL-10, IL-12, IFN-gamma, or TNF-alpha with 5 mg of cytokine-specific neutralizing rabbit IgG revealed that IFN-gamma and TNF-alpha were required for maximal IL-1ra production by Mphi
Gasperini et al., AIDS 1998 (HIV Infections) : In contrast, release of IL-1beta and IL-1ra ( IL-1 receptor antagonist ) in response to LPS, or LPS plus IFNgamma , was found to be lower in PMN from HIV positive patients than in PMN from controls, but was significant only in the case of IL-1ra
Kovalovsky et al., Eur J Immunol 1998 : In the present work we examined the regulation of IL-1Ra by Th1 cytokine IFN-gamma , Th2 cytokine IL-4, glucocorticoids and IL-1 in human monocytes
Liu et al., J Immunol 1998 : However, IFN-gamma also suppresses the expression of IFN-beta- and IL-4 induced IL-1Ra so that IFN-gamma may enhance or suppress IL-1 activity depending on the other cytokines present