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CA2 — NOX5
Text-mined interactions from Literome
Bánfi et al., J Biol Chem 2004
:
Mechanism of
Ca2+ activation of the
NADPH oxidase 5 (NOX5)
Oommen et al., Biochem Pharmacol 2004
:
CA also inhibited the store operated influx of Ca2+ into control neutrophils treated with 1 microM thapsigargin, a selective
inhibitor of the endomembrane
Ca2+-ATPase , which does not activate
NADPH oxidase
Cheranov et al., Am J Physiol Cell Physiol 2006
(Calcium Signaling) :
TNF-alpha dilates cerebral arteries via
NAD ( P ) H oxidase dependent
Ca2+ spark activation
Mayer et al., FEBS Lett 1991
:
We found that the purified enzyme also contains FAD, FMN and non-heme iron in equimolar amounts and exhibits striking activities, including a
Ca2+/calmodulin dependent
NADPH oxidase activity, leading to the formation of hydrogen peroxide at suboptimal concentrations of L-arginine or H4biopterin
Potocký et al., New Phytol 2007
:
Exogenous CaCl2 increased NBT reduction at the pollen tube tip, suggesting that
Ca2+ increases the activity of pollen
NOX in vivo
Takeda et al., Science 2008
:
We found that
Ca2+ , in turn,
activated the RHD2
NADPH oxidase to produce ROS at the growing point in the root hair
Glian'ko et al., Prikl Biokhim Mikrobiol 2013
:
It is concluded that
Ca2+ and reactive oxygen species are
involved in the regulation of the membrane
NADPH oxidase activity in roots of pea seedlings
Rossi et al., J Immunol 1989
:
These findings indicate that the activation of phosphoinositide turnover, the liberation of arachidonic acid, the rise in
[Ca2+ ] i, and the activity of protein kinase C are not necessarily
required for ingestion of Con A-opsonized particles and for associated activation of the
NADPH oxidase , the enzyme responsible for the respiratory burst
Sakata et al., Biochem Biophys Res Commun 1987
:
The calmodulin inhibitor, N- ( 6-aminohexyl ) -5-chloro-1-naphthalene sulfonamide ( W-7 ), or trifluoperazine inhibited not only Fc gamma-receptor mediated cytosolic free
Ca2+ increase and O2- generation in macrophages, but also an arachidonate induced
activation of
NADPH-oxidase in a cell-free system
Suzuki et al., J Biol Chem 1985
:
Enhancement by
Ca2+ or Mg2+ of catalytic activity of the superoxide producing
NADPH oxidase in membrane fractions of human neutrophils and monocytes
Aviram et al., FEBS Lett 1983
:
Activation of
NAD ( P ) H oxidase is inhibited by preincubation of neutrophils with 2-deoxyglucose and does not
require the presence of extra cellular
Ca2+
Torres et al., Plant J 1998
:
A putative EF-hand Ca ( 2+ ) -binding motif in the extended N-terminal region of the Atrboh proteins suggests a direct regulatory
effect of
Ca2+ on the activity of the
NADPH oxidase in plants
Watson et al., Biochem Biophys Res Commun 1998
:
Stimulation of primed neutrophils by soluble immune complexes : priming leads to enhanced intracellular
Ca2+ elevations, activation of phospholipase D, and
activation of the
NADPH oxidase