Gene interactions and pathways from curated databases and text-mining

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HSPD1 — IL10

Text-mined interactions from Literome

Kallmann et al., Diabetologia 1999 (Diabetes Mellitus, Type 1...) : The IL-10 response to hsp60 was higher in twins at low disease risk ( islet cell antibody negative ) than in their diabetic cotwins ( p < 0.01 ), as was the IL-4 response to phytohaemagglutinin ( p < 0.05 )
Bajramović et al., J Neuroimmunol 2000 : Hsp60 expression was found to be enhanced in response to cytokines as diverse as IL-1beta, TNF-alpha, IL-4, IL-6 and IL-10
van Halteren et al., J Immunol 2000 (Diabetes Mellitus, Type 1...) : In time, increasing levels of hsp60 induced IL-10 could be detected in NOD mice, but not in age- and MHC class II-matched BiozziABH mice, which lack any sign of pancreatic inflammation ... Genetically protected NOD-asp mice, showing a less progressive development of insulitis, demonstrated a similar increase in hsp60 induced IL-10 in time compared with wild-type NOD mice
Kinnunen et al., Clin Exp Immunol 2003 (Chlamydia Infections...) : Chlamydia trachomatis heat shock protein-60 induced interferon-gamma and interleukin-10 production in infertile women
van Puijvelde et al., Arterioscler Thromb Vasc Biol 2007 (Atherosclerosis...) : The production of interleukin (IL)-10 and transforming growth factor ( TGF ) -beta by lymph node cells in response to HSP60 was observed after tolerance induction
Aalberse et al., PloS one 2011 : Stimulation of CBMC with HSP60 led to CD4 ( + ) T cell proliferation and the production of various cytokines, most notably IL-10 , Interferon-gamma, and IL-6