Perrotti et al., Nat Genet 2002
(Blast Crisis...) :
BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2
Schuster et al., Blood 2003
:
Importantly, incubation of 32D ( Bcr-Ablwt ) cells with the kinase inhibitor imatinib mesylate prior to G-CSF stimulation completely neutralized the effects of Bcr-Abl on granulocytic differentiation and on C/EBPalpha and C/EBPepsilon expression