◀ Back to NFKB1
KRT15 — NFKB1
Text-mined interactions from Literome
Brinkmann et al., J Virol 2007
:
K15 interacts with cellular proteins, TRAF ( tumor necrosis factor receptor associated factor ) and Src kinases, and
activates AP-1,
NF-kappaB , and the mitogen activated protein kinases ( MAPKs ) c-jun-N-terminal kinase and extracellular signal regulated kinase
Wang et al., J Gen Virol 2007
(MAP Kinase Signaling System) :
Similarly to K15-P,
K15-M induces the activation of the Erk2 and JNK1 kinases, the
NF-kappaB transcription factor and the expression of a similar range of cellular inflammatory genes, as assessed by gene-expression microarray studies and reporter assays
Tsai et al., J Virol 2009
:
K15M localizes to lysosomal membranes and
induces cell migration, invasion, and
NF-kappaB ( but not AP-1 ) activity via its conserved SH2 binding motif