Gene interactions and pathways from curated databases and text-mining

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NFKB1 — XRCC5

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Lim et al., J Biol Chem 2004 (Stomach Neoplasms) : Previously, we showed that the expression of Ku antigen , a DNA repair protein, is mediated by NF-kappaB in gastric cancer AGS cells ( Lim, J. W., Kim, H., and Kim, K. H. ( 2002 ) J. Biol. Chem. 277, 46093-46100 )
Kim et al., Amino Acids 2008 (Stomach Neoplasms) : Both Ku70 and Ku80 expressions are mediated by constitutively activated NF-kappaB and constitutively expressed cyclooxygenase-2 in gastric cancer cells, which may be related to gastric cell proliferation and carcinogenesis
Ravi et al., Mol Cell Biochem 2008 (Melanoma) : In addition, our study shows that ATM, but not ATM-Rad3 related (ATR) or DNA dependent protein kinase (DNA-PK) is involved in UV-induced NF-kappaB activation
Teo et al., Nat Cell Biol 2010 : NF-kappaB is induced by ectopic expression of Rap1 , whereas its activity is inhibited by Rap1 depletion ... Furthermore, levels of Rap1 are positively regulated by NF-kappaB , and human breast cancers with NF-kappaB hyperactivity show elevated levels of cytoplasmic Rap1
Basu et al., Biochem Biophys Res Commun 1998 (Glioma) : The role of DNA-PK , a protein kinase involved in the response to DNA damage, in the activation of NF kappa B by IR and TNF alpha was examined ... In HeLa cells, wortmannin, an inhibitor of DNA-PK , blocked the induction of NF kappa B by IR but not by TNF alpha