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CXCL12 — EGF
Text-mined interactions from Literome
Azenshtein et al., Cancer Lett 2005
(Breast Neoplasms...) :
EGF potently
up-regulated CXCL8 secretion by breast tumor cells, and its effect was promoted by a consecutive treatment of the cells by estrogen and progesterone
Guo et al., Colloids Surf B Biointerfaces 2007
(Neoplasm Metastasis...) :
In this research, the result first showed that
epidermis growth factor (EGF) enhanced the expression of CXCR4 and the migration of ovarian cancer cells, moreover, both
stromal cell derived factor-1alpha ( SDF-1alpha ) and EGF induced high matrix metallopeptidase 9 (MMP9) expressions
Sciaccaluga et al., Am J Physiol Cell Physiol 2010
(Brain Neoplasms...) :
Furthermore, we demonstrate that both CXCL12 and
EGF induce Ca ( 2+ ) mobilization and IK ( Ca ) channel activation but only
CXCL12 induces a long-term upregulation of the IK ( Ca ) channel activity
Haim et al., Neoplasia (New York, N.Y.) 2011
(Breast Neoplasms) :
We found that stimulation by
EGF alone
induced the release of
CXCL8 through signaling pathways involving ErbB2, ErbB1, Erk, and phosphoinositide 3-kinase (PI3K)
Son et al., Journal of inflammation (London, England) 2013
:
Finally, CCL20 and
CXCL8 responded synergistically in
response to
EGF and TNF in OVCAR-3 and SKOV-3 cells