Ouchi et al., Circulation 2000
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Adiponectin , an adipocyte derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP dependent pathway ... Adiponectin suppressed TNF-alpha induced IkappaB-alpha phosphorylation and subsequent NF-kappaB activation without affecting other TNF-alpha mediated phosphorylation signals, including Jun N-terminal kinase, p38 kinase, and Akt kinase
Tomizawa et al., Diab Vasc Dis Res 2008
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Adiponectin induces NF-kappaB activation that leads to suppression of cytokine induced NF-kappaB activation in vascular endothelial cells : globular adiponectin vs. high molecular weight adiponectin