Jono et al., J Biol Chem 2003
:
Activation of TGF-beta-Smad signaling, however, leads to down-regulation of p38 by inducing MAPK phophatase-1, thereby acting as a negative regulator for MUC5AC induction
Kamaraju et al., J Biol Chem 2005
(Breast Neoplasms...) :
We show that Smad2/3 are indispensable for TGF-beta mediated growth inhibition, and that both p38 and Rho/ROCK pathways affect the linker region phosphorylation of Smad2/3