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TDG — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: TDG — TP53 (direct interaction, two hybrid) Minty et al., J Biol Chem 2000

Text-mined interactions from Literome

Kim et al., Biochem Biophys Res Commun 2008 : Further, TDG enhanced the p53 or p73alpha induced growth repression
da Costa et al., Cell cycle (Georgetown, Tex.) 2012 : Transcriptional regulation of thymine DNA glycosylase (TDG) by the tumor suppressor protein p53 ... Here we show that wild-type p53 transcriptionally regulates TDG expression ... Overall, our results show that TDG expression is directly regulated by p53 , suggesting that loss of p53 function may affect processes mediated by TDG, thus negatively impacting on genetic and epigenetic stability