Gene interactions and pathways from curated databases and text-mining

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DAB2 — PRKCD

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: DAB2 → PRKCD (directlyIncreases, DAB2 Activity) Tseng et al., J Biol Chem 1999*
    Evidence: DOC-2/DAB2, a novel phosphoprotein with signal-transducing capability, inhibits human prostatic cancer cells (Tseng, C.-P., Ely, B. D., Li, Y., Pong, R.-C., and Hsieh, J.-T. (1998) Endocrinology 139, 3542-3553). However, its mechanism of action is not understood completely. This study delineates the functional significance of DOC-2/DAB2 protein phosphorylation and demonstrates that in vivo activation of protein kinase C (PKC) by 12-O-tetradecanoylphorbol-13-acetate (TPA) induces DOC-2/DAB2 phosp...

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *