Gene interactions and pathways from curated databases and text-mining

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CD4 — HSPD1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Wang et al., Eur J Immunol 2009 (Schistosomiasis japonica) : The aim of this study was to determine the mechanism behind the induction of CD4 ( + ) CD25 ( + ) T cells by Schistosoma japonicum HSP60 ( SjHSP60 ) -derived peptide SJMHE1 as well as to elucidate the cellular and molecular basis for the induction of CD4 ( + ) CD25 ( + ) T cells during S. japonicum infection
Aalberse et al., PloS one 2011 : Stimulation of CBMC with HSP60 led to CD4 ( + ) T cell proliferation and the production of various cytokines, most notably IL-10, Interferon-gamma, and IL-6
Kapitein et al., Cell Stress Chaperones 2013 (Dermatitis, Atopic) : However, despite their regulatory phenotype, hsp60 induced CD4 ( + ) CD25 ( bright ) CD127 ( - ) FOXP3 ( + ) T cells of AD patients were incapable of suppressing effector T cells in vitro