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Text-mined interactions from Literome

Andela et al., Cancer Res 2000 (Adenocarcinoma, Bronchiolo-Alveolar...) : The NFkappaB signal blockade resulted in the down-regulation of prometastatic matrix metalloproteinase 9, a urokinase-like plasminogen activator, and heparanase and reciprocal up-regulation of antimetastatic tissue inhibitors of matrix metalloproteinases 1 and 2 and plasminogen activator inhibitor 2
Yang et al., Chin J Cancer 2003 (Adenocarcinoma...) : The current study was designed to investigate the effect of eIF-4E on the expression and activity of NF-kappaB and observe how the activity level of NF-kappaB contributes , as a secondary effect, to the transcription of heparanase in human colon adenocarcinoma LS-174T cells ... Furthermore, this down regulation of the ubiquitous transcription factor NF-kappaB led to reduced transcription of the heparanase gene, and the transfected cells also showed a considerable decrease in heparanase protein and activity