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CTGF — MYLIP

Text-mined interactions from Literome

Duisters et al., Circ Res 2009 (Disease Models, Animal...) : miR-133 and miR-30 regulate connective tissue growth factor : implications for a role of microRNAs in myocardial matrix remodeling
Yang et al., Oncogene 2012 (Carcinoma, Squamous Cell...) : Ectopic miR-504 increased migration and invasion in SAS/CTGF-M3 , however, miR-346 did not have such impact on migration/invasion
Xiao et al., Mol Ther 2012 (Disease Models, Animal...) : Interestingly, overexpression of miR-29 could in turn negatively regulated TGF-ß and connective tissue growth factor (CTGF) expression and Smad3 signaling
Adam et al., Basic Res Cardiol 2012 (Fibrosis) : A small molecule inhibitor of lysyl oxidase, BAPN, prevented the AngII as well as the CTGF induced miR-21 expression
Fox et al., RNA 2013 (Glioblastoma) : The unexpected effects of miR-18a on CTGF transcription are mediated in part by direct targeting of Smad3 and ensuing weakening of TGFß signaling
Lee et al., PloS one 2013 (Brain Neoplasms...) : In addition miR-145 regulates glioma cell migration by targeting CTGF which downregulates SPARC expression
Yu et al., Cell death & disease 2013 (Cell Transformation, Neoplastic...) : Loss of connective tissue growth factor as an unfavorable prognosis factor activates miR-18b by PI3K/AKT/C-Jun and C-Myc and promotes cell growth in nasopharyngeal carcinoma ... Subsequently, we discovered that the reduction of CTGF increased the expression of miR-18b , an oncomir promoting cell proliferation ... Finally, we further found that miR-18b directly suppressed the expression of CTGF in NPC ... Further, we discovered that attenuated CTGF mediated upregulation of miR-18b was dependent on the increased binding of transcription factors Jun proto-oncogene (C-Jun) and v-Myc myelocytomatosis viral oncogene homolog ( C-Myc ) to miR-18b promoter region via phosphoinositide 3-kinase (PI3K)/AKT pathway