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IFNG — MNAT1

Text-mined interactions from Literome

Vaidyanathan et al., Cytokine 2001 : The data suggest that LPS-inducible p35 synthesis from exon 1 p35 transcripts leads to greater amount of bioactive IL-12 than IFN-gamma/CD40 induced p35 expression from alternate p35 exon 1a/exon 2 transcripts
Nakano et al., Blood 2007 (Bacterial Infections...) : The transcription levels of p35 and p40 were increased by stimulation of BMMCs with IFN-gamma/lipopolysaccharide (LPS)
Qi et al., Sci China C Life Sci 2000 : Taken together, the data suggest : ( i ) IFN-gamma/LPS could strongly induce the expression of IL-12 p40 and p35 mRNA ; both the expression levels were equal ; this phenomenon coincided with the high-level secretion of IL-12 p70 induced by IFN-gamma/LPS ; ( ii ) NF-kappaB signal pathway is essential for IFN-gamma/LPS to induce IL-12 mRNA expression ; ( iii ) by blocking the degradation of IkappaB, the PSI suppresses the IL-12 p40/p35 mRNA expression induced by LPS and IFN-gamma/LPS ; ( iv ) NF-kappaB signal may not be involved in the mechanism by which IFN-gamma enhanced the expression of the LPS induced IL-12 p40/p35 mRNA
Snijders et al., J Immunol 1996 : The effects of IFN-gamma , IL-10, and IL-4 on the p35 mRNA expression in LPS stimulated purified monocytes were similar to the effects of these cytokines on p70 protein production, and the p40 mRNA expression corresponded to p40 protein production
Hayes et al., Blood 1998 (Cell Transformation, Viral) : Interferon-gamma dependent inducible expression of the human interleukin-12 p35 gene in monocytes initiates from a TATA containing promoter distinct from the CpG-rich promoter active in Epstein-Barr virus transformed lymphoblastoid cells