Gene interactions and pathways from curated databases and text-mining

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RB1 — RBL2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Jiang et al., Oncogene 2000 (Bone Neoplasms...) : pRB induced cellular p130 levels while p107 repressed them
Lee et al., Cancer Cell 2002 (Cell Transformation, Neoplastic...) : Biochemical analyses suggest that this tumor suppression occurs via a novel mechanism : E2F4 loss allows p107 and p130 to regulate the pRB-specific , activator E2Fs