Gene interactions and pathways from curated databases and text-mining

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JAK2 — MMP13

Text-mined interactions from Literome

El Mabrouk et al., Biochim Biophys Acta 2007 : Janus kinase 2 (JAK2) inhibitor, AG490, suppressed OSM induced ADAMTS-4 mRNA expression but did not affect MMP-13 levels while JAK3 pharmacological inhibitor and siRNA transfection suppressed both
Huang et al., Rheumatology (Oxford) 2011 (Osteoarthritis) : Both janus kinase 2 (JAK2) and JAK3 inhibitors suppressed AGE induced MMP-13 , ADAMTS-4 and ADAMTS-5 expression and enzyme activity