Häcker et al., Nat Rev Immunol 2011
:
In this Review, we discuss our current understanding of the role of TRAF3 in TNFR and TLR signalling pathways, and its role in disease
Clark et al., Proc Natl Acad Sci U S A 2011
:
Toll-like receptor ( TLR ) ligands that signal via TIR-domain containing adapter inducing IFNß ( TRIF ) activate the I?B kinase ( IKK ) -related kinases, TRAF associated NF?B activator ( TANK) binding kinase-1 (TBK1 ) and IKKe, which then phosphorylate IRF3 and induce the production of IFNß