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ARG1 — IL12B

Text-mined interactions from Literome

Shweash et al., Mol Immunol 2011 (Leishmaniasis) : These data demonstrate for the first time the role of TLR-4 in mediating the effects of L. mexicana promastigotes on MAP kinase activation, up-regulation of COX-2, iNOS as well as arginase-1 expression in macrophages and further shows that PGE ( 2 ), NO and arginase activity all contribute substantially to the inhibition of host cell IL-12 production
Nelius et al., Prostate 2013 (Prostatic Neoplasms...) : Finally, PEDF stimulated the expression of iNOS, IL12 , and TNFa ; and inhibited IL10 and arginase 1 in mouse and human macrophages confirming a M1-type differentiation
Thakur et al., Journal of translational medicine 2013 (Pancreatic Neoplasms) : Reduced accumulation of MDSC was accompanied by significantly lower levels of COX2 ( p < 0.0048 ), PGE2 ( p < 0.03 ), and their downstream effector molecule Arginase-1 ( p < 0.01 ), and significantly higher levels of TNF-a, IL-12 and chemokines CCL3, CCL4, CCL5, CXCL9 and CXCL10 under aATC induced Th1 cytokine enriched microenvironment