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CNTN2 — VCAM1

Text-mined interactions from Literome

Valentin et al., J Gen Virol 2001 : These data establish that VCAM-1 induced by Tax on T-cells thus contributes to the immunopathological process triggered by HTLV-1 infection
Valentin et al., J Virol 1997 (HTLV-I Infections) : The role of the viral trans-activator Tax protein in the induction of VCAM-1 was first indicated by the detection of this adhesion molecule on Jurkat T-cell clones stably expressing the tax gene ... The effect of Tax on VCAM-1 gene transcription was next confirmed in JPX-9 cells, a subclone of Jurkat cells, carrying the tax sequences under the control of an inducible promoter ... Collectively, these results therefore suggest that the exclusive Tax induced expression of VCAM-1 on T cells may represent a pivotal event in the progression of HTLV-1 associated diseases