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NFKB1 — PLCG1

Text-mined interactions from Literome

Kim et al., FEBS Lett 2000 : To directly define the role of phospholipase Cgamma1 ( PLCgamma1 ) in NF-kappaB activation, NF-kappaB promoted luciferase reporter gene plasmid ( pNF-kappaB-Luc ) was transfected into rat-3Y1 fibroblasts that overexpress whole PLCgamma1 ( PLCgamma1-3Y1 ), src homology domains SH2-SH2-SH3 of PLCgamma1 ( SH223-3Y1 ) and v-src ( Src-3Y1 )
Yamamoto et al., FEBS Lett 2001 : These results imply that PLC-gamma1 may play a critical role in a hematopoietic cell-specific adapter protein mediated NF-AT and NF-kappaB activation in a non-lymphoid cell
Li et al., Life Sci 2005 (Colorectal Neoplasms) : These data indicated that PLCgamma1 played a pivotal role in the migration of human colorectal cancer cell and first demonstrated that upregulation of NF-kappaB binding activity and downregulation of Hsp70 expression were PLCgamma1 dependent in LoVo cells
Yang et al., J Biol Chem 2008 (MAP Kinase Signaling System) : Lastly, we examined the role of the immediate-early transcription factors AP-1 and NF-kappaB and have found that phospholipase C-gamma dependent c-Jun and ERK dependent c-fos, but not the NF-kappaB , are strongly activated by bFGF, which in turn regulates the neuronal differentiation of BMSCs
Fu et al., J Exp Med 2010 (Autoimmune Diseases...) : We demonstrate that PLCgamma1 deficiency affects positive and negative selection, significantly reduces single positive thymocytes and peripheral T cells, and impairs TCR induced proliferation and cytokine production, and the activation of ERK, JNK, AP-1, NFAT, and NF-kappaB