Ossipova et al., Nat Cell Biol 2003
:
LKB1 ( XEEK1 ) regulates Wnt signalling in vertebrate development ... These studies show that LKB1/XEEK1 is required for Wnt-beta-catenin signalling in frogs and mammals and provides novel insights into its role in vertebrate developmental patterning and carcinogenesis
Ma et al., Oncol Rep 2010
(Adenocarcinoma...) :
These findings suggest that Wnt signaling may be activated in a subset of PJSs, and activation of the Wnt/beta-catenin signaling in PJS polyps may be caused by LKB1 expression