Gene interactions and pathways from curated databases and text-mining

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GGT1 — NFKB1

Text-mined interactions from Literome

Maellaro et al., J Cell Sci 2000 (Melanoma) : In addition, GGT expression results in an up-regulation of the transcription factor NF-kappa B , which could explain the higher metastatic behaviour reported for GGT-rich melanoma cells as compared to their GGT-poor counterparts
Djavaheri-Mergny et al., Mol Cell Biochem 2002 : Moreover, we show that lipid peroxidation is involved in GGT dependent NF-kappaB activation since vitamin E, which completely inhibits GGT induced generation of lipid peroxides, prevents the GGT dependent NF-kappaB activation ... This finding suggests that GGT mediated NF-kappaB activation plays a role in the control of apoptosis in U937 cells