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HDAC5 — PPARGC1A

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: Complex of 63 proteins (association, anti bait coimmunoprecipitation) Miles et al., Mol Cell Proteomics 2005

Text-mined interactions from Literome

Czubryt et al., Proc Natl Acad Sci U S A 2003 (Death, Sudden, Cardiac) : The transcriptional coactivator PGC-1 alpha , a master regulator of mitochondrial biogenesis and fatty acid oxidation, was also down-regulated in response to HDAC5 expression
Takemori et al., Endocr J 2009 : These observations suggest that GSK-3 beta and SIK1 may play important roles in the regulation of PGC-1alpha gene expression by inactivating HDAC5 followed by activation of MEF2C