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C14ORF166 — IL5

Text-mined interactions from Literome

Thomas et al., Eur J Biochem 1999 : This requires the contribution of several promoter elements ; however, the conserved lymphokine element 0 (CLE0) in particular, is essential for expression of IL-5
Schwenger et al., J Biol Chem 2002 : This study has utilized the activation of different transcription factors by different stimuli in a human T-cell line to study the role of conserved lymphokine element 0 (CLE0) in the specific induction of IL5
Arthaningtyas et al., Growth Factors 2005 : CLE0 is also the main target for IL-5 inhibition by dexamethasone, and we present evidence consistent with a role of GILZ in this
Siegel et al., J Biol Chem 1995 (Lymphoma) : Taken together, our data suggest that activation via the unique sequence combination GATA/CLE0 results in selective expression of the IL-5 gene in response to elevated levels of intracellular cAMP
Yamagata et al., Mol Cell Biol 1997 (Leukemia, T-Cell) : A deletion construct of the promoter indicated that the -75 GATA element and CLE0 are sufficient to mediate synergistic activation of the IL-5 promoter