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ESAT — IL10
Text-mined interactions from Literome
Menon et al., J Interferon Cytokine Res 2002
:
The presence of
ESAT-6 as a fusion partner with P71 during immunization, however,
resulted in an enhanced P71-specific IFN-gamma response, decreased release of
IL-10 , and significantly greater ( p < 0.05 ) IgG2a antibody levels in comparison to immunizing with P71 alone
Al-Attiyah et al., FEMS Immunol Med Microbiol 2006
(Tuberculosis, Pulmonary) :
The secretion of IFN-gamma, but not
IL-10 , in the
presence of Ag85B,
ESAT6 and MPT64 supports their potential as subunit vaccine candidates against TB
Peng et al., J Biol Chem 2011
(Latent Tuberculosis) :
SB203580 did not reverse
ESAT-6 mediated inhibition of IL-17 and
IL-10 production, suggesting a specific effect of SB203580 on IFN-? production
Pinheiro et al., Clin Exp Immunol 2013
(Tuberculosis, Multidrug-Resistant...) :
In addition, increased
IL-10 secretion was
observed in cultured MDR-TB cells following
ESAT-6 stimulation, but not in NR-TB or NTM patients