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IL3 — LTB
Text-mined interactions from Literome
Rola-Pleszczynski et al., Union Med Can 1989
:
In particular,
LTB4 can induce suppressor cells, activate the synthesis and production of lymphokines such as interleukin 2 or interferon-gamma,
stimulate the production of
interleukin 1 by monocytes or macrophages, and activate cytotoxic cells against virus infected or tumor target cells
Matsumoto et al., Prostaglandins Leukot Essent Fatty Acids 1995
(Leukemia, Basophilic, Acute) :
IL-3 and IL-5
enhance the production of
LTB4 stimulated by calcium ionophore in rat basophilic leukemia cells ... These results suggest that
IL-3 and IL-5
increase the production of
LTB4 by priming the activity of phospholipase A2(PLA2) without inducing enzymes in the arachidonate 5-lipoxygenase pathway