Gene interactions and pathways from curated databases and text-mining

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MYCN — PIK3CA

Text-mined interactions from Literome

Chesler et al., Cancer Res 2006 (Neuroblastoma) : Consistent with these observations, PI3K inhibition in MYCN amplified human neuroblastoma cell lines resulted in decreased levels of Mycn protein without affecting levels of MYCN mRNA and caused decreased proliferation and increased apoptosis
Kang et al., Oncogene 2008 (Neovascularization, Pathologic...) : N-myc is a novel regulator of PI3K mediated VEGF expression in neuroblastoma