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IL15 — STAT4
Text-mined interactions from Literome
Chin et al., Nature 2002
(Listeriosis...) :
Furthermore, Rip2 deficiency results in impaired interferon-gamma production in both TH1 and natural killer cells, attributed in part to defective
interleukin-12 induced
Stat4 activation
Strengell et al., J Immunol 2003
:
We also show that
IL-15 activated the binding of STAT1, STAT3,
STAT4 , and STAT5 to the regulatory sites of the IFN-gamma gene
Karpuzoglu et al., Endocrinology 2009
:
Signal transducer and activation of transcription ( STAT ) 4beta, a shorter isoform of
interleukin-12 induced
STAT4 , is preferentially activated by estrogen
Watford et al., J Exp Med 2008
(Toxoplasmosis, Animal) :
We investigated the potential roles of Tpl2 in T cells and found that it was induced by
interleukin-12 in human and mouse T cells in a
Stat4 dependent manner
Thierfelder et al., Nature 1996
:
Requirement for
Stat4 in
interleukin-12 mediated
responses of natural killer and T cells
GarcĂa et al., J Immunol 1998
:
Moreover, we showed that this increase in IFN-gamma could be explained by the dual
activation of STAT1 and
STAT4 by
IL-15 and IL-12, respectively