Gene interactions and pathways from curated databases and text-mining

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HIF1A — SLC22A3

Text-mined interactions from Literome

Jiang et al., Int J Urol 2007 (Cell Transformation, Neoplastic...) : This may be the critical factor that directly controls the process of EMT induced by HIF-1alpha in prostate cancer cells
Luo et al., Zhonghua Nan Ke Xue 2008 (Neoplasm Invasiveness...) : [ Over-expression of HIF-1alpha induces EMT of human prostate cancer cells ] ... The over-expression of HIF-1alpha could induce EMT in the human prostate carcinoma cell line LNCaP and enhance its invasiveness through E-cadherin and vimentin regulation
Copple et al., Liver Int 2010 : To determine whether HIF-1alpha contributes to EMT in the liver during the development of fibrosis, control and HIF-1alpha-deficient mice were subjected to BDL
Wu et al., Zhonghua Nan Ke Xue 2010 (Prostatic Neoplasms) : Slug may be one of the key transcription factors involved in the HIF1alpha induced EMT of LNCaP cells, while ZEB1 and Slug may play an important role in repressing the epithelial phenotype of the ARCaP model
Luo et al., Zhonghua Yi Xue Za Zhi 2010 (Cell Transformation, Neoplastic...) : Our previous study has successfully proved that over-expression of HIF-1alpha could induce EMT in LNCaP cells, but not in PC-3 ... And it may be one critical factor directly controlling the process of EMT induced by HIF-1alpha in prostate cancer