Gene interactions and pathways from curated databases and text-mining

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GRB2 — TNF

Text-mined interactions from Literome

Huh et al., Immunol Lett 2003 (Arthritis, Rheumatoid) : Regulation of GRB2 and FLICE2 expression by TNF-alpha in rheumatoid synovium ... Thus, these results suggest that over-expression of GRB2 and FLICE2 in RA synovium is caused by TNF-alpha inducibility differentially regulated in RA synoviocytes and provide potential pathogenic roles of these genes in the hyperplasia of the RA synovium
Guilloton et al., Cell Signal 2007 (Leukemia, Myeloid, Acute) : The effects of TNFalpha and FasL on GrB expression were specifically mediated by p38MAPK ( Mitogen-activated-protein-kinase ) activation
Kim et al., Int Immunopharmacol 2007 (Arthritis, Experimental...) : G-Rb1 significantly inhibited TNF-alpha upregulation in PBMCs, FLS and chondrocytes induced by IFN-gamma, LPS or IL-1
Lee et al., Phytother Res 2013 (Inflammation) : GRb1 significantly reduced the upregulation of tumor necrosis factor-a , interleukin (IL)-1ß and IL-6 mRNA in the brain tissue at 4?h after LPS injection