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IL1A — SRC

Text-mined interactions from Literome

Funakoshi-Tago et al., Eur J Biochem 2003 : We found that IL-1 mediated c-Src activation was required for AP-1 activation, but not for NF-kappa B activation and also revealed that c-Src induced AP-1 activation was enhanced synergistically by the coexpression of TNF receptor associated factor 6 (TRAF6) ... In addition, c-Src interacts with TRAF6 in response to IL-1 and this interaction is required for c-Src activity
Wang et al., J Biol Chem 2005 : Because the non-receptor tyrosine phosphatase Src homology 2 domain containing protein tyrosine phosphatase-2 ( SHP-2 ) is enriched in focal adhesions and IL-1 induced ERK activation requires increased Ca ( 2+ ), we determined whether SHP-2 modulates IL-1 induced Ca ( 2+ ) signaling
Chen et al., Neurochem Int 2011 : Pharmacological studies revealed that the integrity of lipid raft and the activation of Src , Ras, Raf, ERK, and NF-?B all contributed to JEV induced TNF-a and IL-1ß expression
Huang et al., J Neurosci 2011 : Additionally, IL-1ß induced Src phosphorylation at 0.01 ng/ml in hippocampal neurons, a dose 1000-fold lower than that used to stimulate inflammatory responses ... In this study, we demonstrate that AcPb specifically mediates IL-1ß activation of p-Src and potentiation of NMDA induced calcium influx in mouse hippocampal neurons in a dose dependent manner
Kondo et al., Arch Biochem Biophys 2013 : SP600125 remarkably suppressed the IL-1 induced phosphorylation of both I?B and NF-?B, whereas SP600125 failed to affect the IL-1 induced phosphorylation of AMPK, STAT3 or Src