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AREG — JUN
Text-mined interactions from Literome
Kato et al., Biochem Biophys Res Commun 2003
(MAP Kinase Signaling System) :
As evidenced by Western blot analysis,
amphiregulin stimulated the phosphorylation of p42/p44-mitogen activated protein kinase ( MAPK ), p38-MAPK,
c-Jun NH2-terminal protein kinase (JNK) , and Akt/protein kinase B (PKB), respectively
Aguiari et al., J Mol Med (Berl) 2012
(Polycystic Kidney, Autosomal Dominant) :
We now show by microarray analysis, luciferase assay, mutagenesis, and chromatin immunoprecipitation that CREB and
AP1 contribute to increased expression of the
amphiregulin gene, which codifies for an epidermal growth factor-like peptide, in ADPKD cystic cells, thereby promoting their cell growth