UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to LCK

LCK — MAP4K1

Pathways - manually collected, often from reviews:

NCI Pathway Database TCR signaling in naïve CD4+ T cells: HPK1 (MAP4K1) → TCR/CD3/MHC II/CD4/LCK/ZAP-70 complex (CD247-CD3E-CD3G-CD3D-HLA-DRA-HLA-DRB1-CD4-LCK-ZAP70) (modification, collaborate)
Liu et al., J Immunol 2000
Evidence: mutant phenotype, physical interaction, other species