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CCK — RAF1

Text-mined interactions from Literome

Piiper et al., Mol Pharmacol 2000 : PTx also inhibited ERK1/2 activation in response to the PKC activator 12-O-tetradecanoylphorbol-13-acetate ( TPA ) and epidermal growth factor (EGF) as well as activation of c-Raf-1 by EGF and CCK
Piiper et al., J Biol Chem 2003 : CCK activated ERK1/2 and Raf-1 to a similar extent as epidermal growth factor (EGF)
Kim et al., J Biol Chem 2012 (Pancreatitis) : Furthermore, we show that either suppression of Raf-1 kinase inhibitory protein expression using short hairpin RNA or gene ablation prevented the sensitizing effects of ethanol on cholecystokinin- and carbachol stimulated Ca ( 2+ ) signaling and intracellular chymotrypsin activation in pancreatic acinar cells, suggesting that the modulation of Raf-1 inhibitory protein expression may have future therapeutic utility in the prevention or treatment of alcohol associated pancreatitis