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CXCL12 — IL2

Text-mined interactions from Literome

Nanki et al., J Immunol 2000 : In addition, SDF-1alpha costimulated proliferation of CD4+ T cells and production of IL-2 , IFN-gamma, IL-4, and IL-10
Nanki et al., Cell Immunol 2001 (MAP Kinase Signaling System) : CXCL12 also induced enhancement of IL-2 production and proliferation by anti-CD3 stimulated CD4+ memory T cells, but not by CD4+ naive T cells
Damås et al., Circulation 2002 (Angina, Unstable) : In vitro, SDF-1alpha ( 500 ng/mL ) reduced both unstimulated and endotoxin/mitogen stimulated mRNA and protein levels of monocyte chemoattractant protein-1, interleukin-8 , matrix metalloproteinase-9, and tissue factor while increasing tissue inhibitor of metalloproteinases-1 in PBMC from patients with unstable angina
Han et al., J Leukoc Biol 2004 (Arteriosclerosis) : lysoPC also enhanced SDF-1 stimulated production of inflammatory cytokines interleukin-2 and interferon-gamma by CD4 T cells activated by anti-CD3 immunoglobulin G