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STAT1 — WNK1
Text-mined interactions from Literome
Wan et al., Nucleosides Nucleotides Nucleic Acids 2010
:
Exposure to IFN-gamma mainly affects nuclear IRF-1 and
STAT1 in EMT6, but
inhibits NF-kappaB
p65 activity, indicating that the cooperative stimulation was the result of the independent activation of NF-kappaB, STAT1 and IRF-1 transcriptional factors through binding to their unique sites in the UPase promoter
Lee et al., Glia 1999
:
These data collectively suggest that in human astrocytes, the
p65 homodimer is responsible for ICAM-1 upregulation upon TNF-alpha or IL-1beta stimulation, and that IFN-gamma enhancement of ICAM-1
involves activation of
STAT-1alpha homodimers